Spike Protein Research

and Education Directive

(SPRED)

The Spike Protein Research and Education Directive (SPRED) is dedicated to solving long COVID and vaccine injury through independent research.

Diagnostics Development

We are developing diagnostic parameters and kits for treatment guidance.

Understanding Mechanism

We are understanding more about how spike protein diseases and how disease processes work - and how to treat them.

Evidence-based therapeutics

We are evaluating different treatments based on both their mechanistic basis and their clinical impact through our network of practitioner-scientists.

Our Team

We are a network of Scientific and Medical Professionals devoted to solving the challenges of long COVID and COVID-19 vaccine injury.


Our member publications


A review on the safety record of mRNA vaccines and pathological mechanisms.

Halma, M.T.J.; Plothe, C.; Marik, P.; Lawrie, T.A. Strategies for the Management of Spike Protein-Related Pathology. Microorganisms 202311, 1308. https://doi.org/10.3390/microorganisms11051308

An overview of spike protein disease mechanism and therapeutics.

Halma, M.; Marik, P.; Saleeby, Y. Exploring Therapeutic Applications of Autophagy in Spike Protein-Related Pathology. Preprints 2023, 2023061306. https://doi.org/10.20944/preprints202306.1306.v1


How spike protein can be cleared via autophagy.

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